Essential Gene Knowledge Graph
| cancer_type | gene | n | e | drug | DrugScore | drug_gene_interaction_source |
|---|---|---|---|---|---|---|
| Low_Grade_Glioma | MET | 0.556 | 13.889 | Palbociclib | 1.000 | DGIdb |
| Pancreatic_Carcinoma | KRAS | 0.913 | 3.533 | Palbociclib | 1.000 | DGIdb |
| Ewing`s_Sarcoma | CDK4 | 0.900 | 3.482 | Palbociclib | 1.000 | DGIdb |
| Ewing`s_Sarcoma | CDK4 | 0.900 | 3.482 | Palbociclib/ribociclib analog 1 | 1.000 | TTD |
| B_Cell_Non_Hodgkin`s_Lymphoma | CDK6 | 0.800 | 3.059 | Palbociclib | 1.000 | DGIdb |
| Low_Grade_Glioma | CDK6 | 0.778 | 2.974 | Palbociclib | 1.000 | DGIdb |
| Neuroblastoma | CDK6 | 0.647 | 2.474 | Palbociclib | 1.000 | DGIdb |
| Plasma_Cell_Myeloma | PIK3CA | 1.000 | 2.407 | Palbociclib | 1.000 | DGIdb |
| Colorectal_Carcinoma | KRAS | 0.600 | 2.321 | Palbociclib | 1.000 | DGIdb |
| Plasma_Cell_Myeloma | CDK6 | 0.600 | 2.294 | Palbociclib | 1.000 | DGIdb |
| Lung_Adenocarcinoma | CDK4 | 0.550 | 2.128 | Palbociclib | 1.000 | DGIdb |
| Lung_Adenocarcinoma | CDK4 | 0.550 | 2.128 | Palbociclib/ribociclib analog 1 | 1.000 | TTD |
| Neuroblastoma | CCND1 | 0.941 | 1.843 | Palbociclib | 1.000 | DGIdb |
| Endometrial_Carcinoma | CDK2 | 0.714 | 1.828 | Palbociclib/ribociclib analog 1 | 1.000 | TTD |
| Gastric_Carcinoma | CDK2 | 0.714 | 1.828 | Palbociclib/ribociclib analog 1 | 1.000 | TTD |
| Esophageal_Adenocarcinoma | PIK3CA | 0.714 | 1.720 | Palbociclib | 1.000 | DGIdb |
| Gastric_Carcinoma | PIK3CA | 0.714 | 1.720 | Palbociclib | 1.000 | DGIdb |
| Pancreatic_Carcinoma | CCND1 | 0.826 | 1.617 | Palbociclib | 1.000 | DGIdb |
| Glioblastoma | CDK2 | 0.625 | 1.599 | Palbociclib/ribociclib analog 1 | 1.000 | TTD |
| Ovarian_Carcinoma | CDK2 | 0.613 | 1.568 | Palbociclib/ribociclib analog 1 | 1.000 | TTD |