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gene
drug
pubchem_cid
pubchem_sid
chembl_id
DrugScore
drug_gene_interaction_source
CDK4
Dexamethasone
5743
46508930
CHEMBL384467
1.000
DGIdb
CDK4
Progesterone
5994
46508968
CHEMBL103
1.000
DGIdb
CDK4
Palbociclib
5330286
8035907; 11062094; 11538604; 12015755; 14808444; 17137183; 39302900; 46394060; 57361299; 78833389; 99436913; 103461613; 103905660; 103905661; 113915142; 121280258; 124360805; 124757012; 125164718; 126580155; 126671645; 126737419; 131480762; 134339015; 134339302; 134339471; 134964422; 135262045; 135686212; 135686213; 135686228; 135686229; 136367313; 136367838; 136920362; 137184856; 137275973; 141483504; 143498887; 144116345; 152240013; 152258827; 152344089; 160647678; 162202562; 164045126; 172232465; 172919351; 177748911; 178103952
CHEMBL189963
1.000
DGIdb
CDK4
Abemaciclib
46220502
96075034; 120483888; 140885353; 141321259; 163621010; 163686341; 172917432; 178103954; 185975428; 198954176; 207011353; 223404298; 223405968; 224401848; 228594084; 242651810; 248540783; 249814531; 251910681; 252215739; 252479469
CHEMBL3301610
1.000
DGIdb
CDK4
Apremilast
11561674
16663888; 28672022; 42703565; 50086920; 78553422; 96025543; 103594774; 104103394; 135195808; 135299279; 136946493; 140792549; 144115618; 152256090; 152258393; 160647230; 164045129; 164194075; 176253765; 178103944; 186014493; 187575333; 189561506; 198938842; 198994002; 218902332; 223380767; 223443866; 223593318; 224603101; 226643371; 247101845; 249492055; 249814467; 250163167; 251962967; 251970550; 252088578; 252160602; 252214744; 252438251; 252451837; 252553654
CHEMBL514800
1.000
DGIdb
CDK4
Alpelisib
56649450
134426754; 140722288; 152159632; 152255399; 152258655; 160647491; 162012035; 163643246; 164041693; 172918746; 174486688; 174861534; 175448776; 176251621; 185965275; 198967672; 215785718; 223382725; 223626250; 225848216; 228076739; 244202215; 249565638; 252214078; 252451646; 252470926
CHEMBL2396661
1.000
DGIdb
CDK4
Nicotine
89594
46506924
CHEMBL3
1.000
DGIdb
CDK4
Trilaciclib
68029831
1.000
TTD
CDK4
Pyrrolo[2,3-d]pyrimidine derivative 9
44818950
1.000
TTD
CDK4
Pyrrolo[2,3-d]pyrimidine derivative 10
53378895
1.000
TTD
CDK4
PMID26161698-Compound-17
739323
1.000
TTD
CDK4
Palbociclib/ribociclib analog 1
89798202
1.000
TTD
CDK4
Oxazolyl methylthiothiazole derivative 1
25195503
1.000
TTD
CDK4
Indole-based analog 13
73293
1.000
TTD
CDK4
Imidazo pyridine derivative 3
46937330
1.000
TTD
CDK4
Ribociclib Succinate
57334219
1.000
TTD
CDK4
chembl:CHEMBL3894860
CHEMBL3894860
1.000
DGIdb
total 17 1 / 1
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