Group CEGE0250

6 genes in 5 organisms

General information
CEG ID:CEGE0250
Function:topoisomerase

CEG_gene IDGene name(s)FunctionConditionUniProtOrganism
CEGE0250_DEG20010853TOP2Essential type II topoisomerase, relieves torsional strain in DNA by cleaving and re-sealing the phosphodiester backbone of both positively and negatively supercoiled DNA; cleaves complementary strands; localizes to axial cores in meiosisRich medium-Saccharomyces cerevisiae
CEGE0250_DEG20040289-topoisomerase 2 mRNARich medium-Danio rerio
CEGE0250_DEG20050277Top2bDNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme)Rich mediumQ64511Mus musculus
CEGE0250_DEG20090744top2DNA topoisomerase IIRich medium-Schizosaccharomyces pombe 972h-
CEGE0250_DEG20100272TOP2Btopoisomerase (DNA) II betaRich mediumQ02880Homo sapiens
CEGE0250_DEG20112491TOP2Atopoisomerase (DNA) II alphaRich mediumP11388Homo sapiens