Group CEGE0793

4 genes in 3 organisms

General information
CEG ID:CEGE0793
Function:Origin Recognition Complex Subunit

CEG_gene IDGene name(s)FunctionConditionUniProtOrganism
CEGE0793_DEG20010043ORC2Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; interacts with Spp1p and with trimethylated histone H3; phosphorylated by Cdc28pRich medium-Saccharomyces cerevisiae
CEGE0793_DEG20010179PDS1Securin, inhibits anaphase by binding separin Esp1p; blocks cyclin destruction and mitotic exit, essential for cell cycle arrest in mitosis in the presence of DNA damage or aberrant mitotic spindles; also required for meiotic progressionRich medium-Saccharomyces cerevisiae
CEGE0793_DEG20030129ORC 2Origin Recognition Complex Subunit 2Rich medium-Arabidopsis thaliana
CEGE0793_DEG20090834orc2origin recognition complex subunit Orc2Rich medium-Schizosaccharomyces pombe 972h-