General information CEG ID: CEG0098 Function: Thymidylate synthase Phyletic Profile: Genes in 18 /29 species: single-copy in18 species and multi-copy in 0 species. In Genus: 14 /20 in GenusShewanella,Vibrio,Staphylococcus,Acinetobacter,Bacteroidaceae,Burkholderia,Porphyromonadaceae,Streptococcus,Caulobacter,Mycoplasma,Pseudomonas,Francisella,Salmonella,EscherichiaIn Family: 12 /18 in FamilyStreptococcaceae,Francisellaceae,Enterobacteriaceae,Moraxellaceae,Mycoplasmataceae,Shewanellaceae,Vibrionaceae,Caulobacteraceae,Pseudomonadaceae,Burkholderiaceae,Staphylococcaceae,BacteroidalesIn Order: 11 /16 in OrderLactobacillales,Alteromonadales,Bacteroidia,Burkholderiales,Vibrionales,Caulobacterales,Thiotrichales,Enterobacteriales,Bacillales,Mycoplasmatales,PseudomonadalesIn Class: 6 /9 in ClassBetaproteobacteria,Gammaproteobacteria,Bacteroidetes,Mollicutes,Bacilli,AlphaproteobacteriaIn Phylum: 4 /5 in PhylumTenericutes,Firmicutes,Proteobacteria,Bacteroidetes/Chlorobi group
CEG_gene ID Gene name(s) Function Pathway Struct Drug ESAHP Organism DEG ID Virulence Protein-Ligand CEG0098 _ 15927008 thyA Thymidylate synthase See pathway sau00240+SA1260 sau00670+SA1260 See drug DB02031 DB02223 DB02256 DB02301 DB02467 DB02752 DB02899 DB03038 DB03157 DB03274 DB03541 DB03558 DB03761 DB03800 DB03818 DB04447 DB04457 DB04503 DB04530 DB04586 DB04696 DB08131 DB01643 DB03685 DB03798 2.0e-066 spu DEG10020157 CEG0098 _ 15640694 thyA thymidylate synthase See pathway vch00240+VC0675 vch00670+VC0675 See drug DB02031 DB02223 DB02256 DB02301 DB02467 DB02752 DB02899 DB03038 DB03157 DB03274 DB03541 DB03558 DB03761 DB03800 DB03818 DB04447 DB04457 DB04503 DB04530 DB04586 DB04696 DB08131 DB01643 DB03685 DB03798 1.5e-037 vch DEG10030143 CEG0098 _ 15902629 thyA Thymidylate synthase See pathway stm00240+STM3001 stm00670+STM3001 See drug DB02031 DB02223 DB02256 DB02301 DB02467 DB02752 DB02899 DB03038 DB03157 DB03274 DB03541 DB03558 DB03761 DB03800 DB03818 DB04447 DB04457 DB04503 DB04530 DB04586 DB04696 DB08131 DB01643 DB03685 DB03798 2.1e-016 stm DEG10070139 CEG0098 _ 118497833 thyA thymidylate synthase See pathway ftn00240+FTN_1248 ftn00670+FTN_1248 See drug DB02031 DB02223 DB02256 DB02301 DB02467 DB02752 DB02899 DB03038 DB03157 DB03274 DB03541 DB03558 DB03761 DB03800 DB03818 DB04447 DB04457 DB04503 DB04530 DB04586 DB04696 DB08131 DB01643 DB03685 DB03798 1.9e-075 ftn DEG10120280 CEG0098 _ 50083753 thyA thymidylate synthase (TS) (TSase) See pathway aci00240+ACIAD0515 aci00670+ACIAD0515 See drug DB02031 DB02223 DB02256 DB02301 DB02467 DB02752 DB02899 DB03038 DB03157 DB03274 DB03541 DB03558 DB03761 DB03800 DB03818 DB04447 DB04457 DB04503 DB04530 DB04586 DB04696 DB08131 DB01643 DB03685 DB03798 3.6e-079 aci DEG10130088 CEG0098 _ 116054070 thyA thymidylate synthase See pathway pau00240+PA14_04480 pau00670+PA14_04480 See drug DB02031 DB02223 DB02256 DB02301 DB02467 DB02752 DB02899 DB03038 DB03157 DB03274 DB03541 DB03558 DB03761 DB03800 DB03818 DB04447 DB04457 DB04503 DB04530 DB04586 DB04696 DB08131 DB01643 DB03685 DB03798 1.5e-077 pau DEG10150011 CEG0098 _ 29143262 thyA thymidylate synthase See pathway spr00240+spr0585 spr00670+spr0585 See drug DB02031 DB02223 DB02256 DB02301 DB02467 DB02752 DB02899 DB03038 DB03157 DB03274 DB03541 DB03558 DB03761 DB03800 DB03818 DB04447 DB04457 DB04503 DB04530 DB04586 DB04696 DB08131 DB01643 DB03685 DB03798 1.2e-074 spr DEG10160195 CEG0098 _ 88195159 thyA thymidylate synthase See pathway stt00240+t2910 stt00670+t2910 See drug DB02031 DB02223 DB02256 DB02301 DB02467 DB02752 DB02899 DB03038 DB03157 DB03274 DB03541 DB03558 DB03761 DB03800 DB03818 DB04447 DB04457 DB04503 DB04530 DB04586 DB04696 DB08131 DB01643 DB03685 DB03798 4.0e-066 stt DEG10170185 CEG0098 _ 16130731 thyA Thymidylate synthase (EC 2.1.1.45) See pathway eco00240+b2827 eco00670+b2827 See struct 1AIQ 1AJM 1AN5 1AOB 1AXW 1BDU 1BID 1BJG 1BQ1 1BQ2 1DDU 1DNA 1EV5 1EV8 1EVF 1EVG 1F4B 1F4C 1F4D 1F4E 1F4F 1F4G 1FFL 1FWM 1JG0 1JTQ 1JTU 1JUT 1KCE 1KZI 1KZJ 1NCE 1QQQ 1SYN 1TDU 1TJS 1TLC 1TLS 1TRG 1TSD 1TSN 1TYS 1ZPR 2A9W 2BBQ 2FTN 2FTO 2FTQ 2G8X 2KCE 2TSC See drug DB02031 DB02223 DB02256 DB02301 DB02467 DB02752 DB02899 DB03038 DB03157 DB03274 DB03541 DB03558 DB03761 DB03800 DB03818 DB04447 DB04457 DB04503 DB04530 DB04586 DB04696 DB08131 DB01643 DB03685 DB03798 4.5e-077 eco DEG10180428 See receptor_ligand 0001472 0001473 0001474 0001475 0001721 0001722 0001801 0002461 0002462 0002463 0002464 0002465 0002466 0003434 0003756 0003830 0003831 0004240 0004241 0004242 0004243 0004244 0004245 0008038 0008039 0008040 0008041 0008704 0008705 0008706 0008707 0008708 0008709 0012478 0012479 0012480 0012481 0012482 0012483 0012484 0012485 0012486 0012487 0014652 0014653 0014654 0025808 0025809 0025810 0025811 0026960 0026961 0026962 0026963 0026964 0026965 0026966 0026967 0026968 0026969 0026970 0026971 0027047 0027048 0027049 0027050 0027051 0027052 0028918 0028919 0028920 0028921 0028922 0028923 0030950 0030951 0030952 0030953 0030954 0030955 0030956 0030957 0030958 0030959 0030960 0030961 0030962 0030963 0030964 0030965 0030966 0030967 0030968 0030969 0030970 0030971 0030972 0030973 0037992 0037993 0037994 0037995 0037996 0037997 0054898 0054899 0054900 0054901 0054902 0054903 0055983 0055984 0055985 0055986 0056729 0056730 0056731 0056732 0056733 0056734 0056768 0056769 0056770 0056771 0056772 0056773 0057204 0057205 0057278 0057279 0057280 0057281 0057282 0057283 0057287 0057288 0057739 0057740 0073751 0073752 0073753 0073754 0073755 0073756 0075329 0075330 0075331 0075332 0075333 0075334 0075335 0075336 0075337 0078406 0078407 0078408 0078409 0078410 0078411 0090233 0090234 0090235 0091265 0091266 0091267 0091268 0101605 0101606 0101607 0101608 0101609 0101610 0114725 0114726 0114727 0114728 0114729 0114730 CEG0098 _ 221235145 thyA thymidylate synthase See pathway ccr00240+CC_2124 ccr00670+CC_2124 See drug DB02031 DB02223 DB02256 DB02301 DB02467 DB02752 DB02899 DB03038 DB03157 DB03274 DB03541 DB03558 DB03761 DB03800 DB03818 DB04447 DB04457 DB04503 DB04530 DB04586 DB04696 DB08131 DB01643 DB03685 DB03798 2.4e-078 ccr DEG10200309 CEG0098 _ 125717921 thyA thymidylate synthase See pathway ssa00240+SSA_1091 ssa00670+SSA_1091 See drug DB02031 DB02223 DB02256 DB02301 DB02467 DB02752 DB02899 DB03038 DB03157 DB03274 DB03541 DB03558 DB03761 DB03800 DB03818 DB04447 DB04457 DB04503 DB04530 DB04586 DB04696 DB08131 DB01643 DB03685 DB03798 2.2e-015 ssa DEG10210109 CEG0098 _ 188995925 thyA thymidylate synthase See pathway pgn00240+PGN_2062 pgn00670+PGN_2062 See drug DB02031 DB02223 DB02256 DB02301 DB02467 DB02752 DB02899 DB03038 DB03157 DB03274 DB03541 DB03558 DB03761 DB03800 DB03818 DB04447 DB04457 DB04503 DB04530 DB04586 DB04696 DB08131 DB01643 DB03685 DB03798 6.3e-081 pga DEG10220458 CEG0098 _ 29347457 thyA thymidylate synthase See pathway bth00240+BT_2047 bth00670+BT_2047 See drug DB02031 DB02223 DB02256 DB02301 DB02467 DB02752 DB02899 DB03038 DB03157 DB03274 DB03541 DB03558 DB03761 DB03800 DB03818 DB04447 DB04457 DB04503 DB04530 DB04586 DB04696 DB08131 DB01643 DB03685 DB03798 9.1e-082 btv DEG10230105 CEG0098 _ 83720929 thyA thymidylate synthase See pathway bte00240+BTH_I1680 bte00240+BTH_II1303 bte00670+BTH_I1680 bte00670+BTH_II1303 See drug DB02031 DB02223 DB02256 DB02301 DB02467 DB02752 DB02899 DB03038 DB03157 DB03274 DB03541 DB03558 DB03761 DB03800 DB03818 DB04447 DB04457 DB04503 DB04530 DB04586 DB04696 DB08131 DB01643 DB03685 DB03798 5.9e-045 bte DEG10240193 CEG0098 _ 15609901 thyA Probable thymidylate synthase ThyA (ts) (TSASE) See pathway mpu00240+MYPU_5380 mpu00670+MYPU_5380 See struct 3QJ7 4FOA 4FOG 4FOX 4FQS See drug DB02031 DB02223 DB02256 DB02301 DB02467 DB02752 DB02899 DB03038 DB03157 DB03274 DB03541 DB03558 DB03761 DB03800 DB03818 DB04447 DB04457 DB04503 DB04530 DB04586 DB04696 DB08131 DB01643 DB03685 DB03798 2.6e-073 mpu DEG10250538 See receptor_ligand 0196659 0196660 0196661 0196662 0196663 0196664 0196665 0196666 0253541 0253542 0253543 0253544 0253545 0253546 0253547 0253548 0253549 0253550 0253551 0253552 0253553 0253554 0253555 0253556 0253557 0253558 0253559 0253560 0253561 0253562 0253563 0253564 0253565 0253566 0253567 0253568 0253569 0253570 0253571 0253572 0253573 0253574 0253575 0253576 0253577 0253578 0253579 0253580 0253581 0253582 0253583 0253584 0253585 0253586 0253587 0253588 CEG0098 _ 24372913 thyA thymidylate synthase ThyA See pathway son00240+SO_1335 son00670+SO_1335 See drug DB02031 DB02223 DB02256 DB02301 DB02467 DB02752 DB02899 DB03038 DB03157 DB03274 DB03541 DB03558 DB03761 DB03800 DB03818 DB04447 DB04457 DB04503 DB04530 DB04586 DB04696 DB08131 DB01643 DB03685 DB03798 3.3e-076 som DEG10290127 CEG0098 _ 378700911 thyA Thymidylate synthase See pathway sey00240+SL1344_2979 sey00670+SL1344_2979 See drug DB02031 DB02223 DB02256 DB02301 DB02467 DB02752 DB02899 DB03038 DB03157 DB03274 DB03541 DB03558 DB03761 DB03800 DB03818 DB04447 DB04457 DB04503 DB04530 DB04586 DB04696 DB08131 DB01643 DB03685 DB03798 1.1e-074 set DEG10320229 CEG0098 _ 53720080 thyA thymidylate synthase See pathway bps00240+BPSL2473 bps00240+BPSS1106 bps00670+BPSL2473 bps00670+BPSS1106 See drug DB02031 DB02223 DB02256 DB02301 DB02467 DB02752 DB02899 DB03038 DB03157 DB03274 DB03541 DB03558 DB03761 DB03800 DB03818 DB04447 DB04457 DB04503 DB04530 DB04586 DB04696 DB08131 DB01643 DB03685 DB03798 1.2e-044 bpk DEG10350305