Information
Gene name:HEM3
Databases ID:DEG :DEG20010149       OrthoDB:EOG09370ONK     UniProt:-
Organism:Saccharomyces cerevisiae
Function:Porphobilinogen deaminase, catalyzes the conversion of 4-porphobilinogen to hydroxymethylbilane, the third step in heme biosynthesis; localizes to the cytoplasm and nucleus; expression is regulated by Hap2p-Hap3p, but not by levels of heme
Nucleotide sequence:Length=984bp
BlastN NCBI nr BlastX NCBI nr BlastN NCBI Human
ATGGGCCCTGAAACTCTACATATTGGTGGGAGAAAATCGAAATTGGCGGTAATACAATCCAACCATGTTTTAAAACTGATCGAAGAAAAGTATCCGGACTACGACTGCAAGGTTTTCACTTTGCAAACTCTTGGTGACCAGATTCAATTCAAACCTTTGTACTCATTTGGCGGTAAAGCTTTATGGACAAAGGAGTTGGAAGACCATCTTTACCATGACGATCCCTCAAAGAAGCTTGACTTGATCGTTCATTCTCTGAAGGACATGCCCACTTTACTACCAGAGGGTTTCGAGCTGGGGGGTATCACTAAGCGGGTCGATCCAACAGATTGTCTTGTCATGCCCTTTTACTCTGCTTATAAGTCTCTGGATGACCTTCCAGACGGGGGGATTGTGGGAACCTCATCCGTGAGAAGATCTGCTCAGCTAAAAAGAAAATACCCACATTTGAAATTTGAAAGTGTCAGAGGAAATATACAAACTAGATTACAAAAACTAGACGACCCAAAATCTCCGTACCAATGCATCATCTTGGCGTCTGCTGGGTTGATGCGTATGGGGTTGGAAAACAGAATTACGCAGCGATTCCATTCGGATACAATGTACCATGCAGTTGGACAAGGCGCCCTGGGTATAGAAATTAGAAAGGGTGACACCAAGATGATGAAGATTCTTGACGAAATTTGCGATCTAAATGCAACTATATGTTGCCTTTCGGAGCGTGCTTTGATGAGAACTTTAGAGGGGGGTTGTTCCGTTCCTATTGGTGTGGAATCTAAATACAATGAAGAGACTAAAAAATTACTATTAAAGGCCATTGTAGTTGACGTTGAAGGCACAGAAGCAGTAGAAGACGAAATTGAAATGCTAATAGAAAATGTTAAAGAAGATTCCATGGCGTGTGGTAAGATACTAGCTGAAAGAATGATTGCCGATGGCGCAAAGAAAATTCTGGATGAAATTAATTTAGACAGAATCAAATGA
Amino acid sequence:Length=327bp
BlastP NCBI nr
MGPETLHIGGRKSKLAVIQSNHVLKLIEEKYPDYDCKVFTLQTLGDQIQFKPLYSFGGKALWTKELEDHLYHDDPSKKLDLIVHSLKDMPTLLPEGFELGGITKRVDPTDCLVMPFYSAYKSLDDLPDGGIVGTSSVRRSAQLKRKYPHLKFESVRGNIQTRLQKLDDPKSPYQCIILASAGLMRMGLENRITQRFHSDTMYHAVGQGALGIEIRKGDTKMMKILDEICDLNATICCLSERALMRTLEGGCSVPIGVESKYNEETKKLLLKAIVVDVEGTEAVEDEIEMLIENVKEDSMACGKILAERMIADGAKKILDEINLDRIK