| Information | |
| Gene name: | HEM12 |
| Databases ID: | DEG :DEG20010166 OrthoDB:EOG09370F05 UniProt:- |
| Organism: | Saccharomyces cerevisiae |
| Function: | Uroporphyrinogen decarboxylase, catalyzes the fifth step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus; a hem12 mutant has phenotypes similar to patients with porphyria cutanea tarda |
| Nucleotide sequence: | Length=1089bp |
| BlastN NCBI nr
BlastX NCBI nr
BlastN NCBI Human
ATGGGTAACTTTCCAGCTCCAAAAAACGATTTGATATTGAGAGCCGCAAAGGGTGAAAAAGTCGAGAGACCGCCATGCTGGATAATGCGCCAGGCAGGTCGTTACCTGCCGGAATATCACGAGGTGAAAAACAATCGTGATTTCTTTCAAACTTGCAGGGATGCGGAAATTGCTTCTGAGATTACTATCCAGCCGGTAAGACGCTATAGAGGCCTCATTGATGCTGCTATTATTTTTAGTGATATCTTAGTTATTCCGCAAGCCATGGGTATGAGGGTCGAGATGCTCGAAGGTAAAGGTCCACATTTCCCAGAACCTTTAAGAAATCCGGAAGACCTCCAAACGGTATTAGACTACAAGGTTGATGTTTTGAAAGAGTTAGATTGGGCTTTCAAGGCAATCACCATGACAAGGATCAAGTTGGATGGTGAGGTTCCCTTATTTGGCTTTTGCGGGGGACCTTGGACTCTAATGGTTTATATGACGGAAGGCGGTGGATCCCGTCTTTTCAGATTTGCCAAACAATGGATTAACATGTATCCAGAGCTTTCTCACAAATTATTACAAAAAATCACTGATGTGGCCGTGGAGTTTCTGAGTCAGCAAGTCGTGGCGGGTGCTCAAATACTACAAGTTTTTGAAAGTTGGGGTGGTGAGCTTTCGTCTGTAGATTTTGATGAGTTTTCCCTACCATATTTAAGACAAATTGCCGAAAGAGTGCCTAAAAGATTGCAAGAATTAGGTATCATGGAACAGATTCCTATGATCGTTTTTGCGAAAGGGTCGTGGTATGCTTTGGACAAGCTATGCTGTTCAGGATTTGACGTTGTTTCGTTGGACTGGTCCTGGGACCCAAGAGAAGCGGTAAAAATAAACAAGAACCGTGTCACCTTGCAGGGCAACCTGGATCCTGGCGTCATGTATGGTTCTAAAGAGGTAATAACAAAGAAAGTTAAACAGATGATTGAGGCTTTTGGAGGTGGGAAGTCCCGCTACATTGTTAATTTCGGTCACGGTACCCACCCTTTCATGGATCCAGACGTCATCAAGTTTTTCTTGGAGGAGTGCCACAGAATTGGTTCGAAGTAA | |
| Amino acid sequence: | Length=362bp |
| BlastP NCBI nr
MGNFPAPKNDLILRAAKGEKVERPPCWIMRQAGRYLPEYHEVKNNRDFFQTCRDAEIASEITIQPVRRYRGLIDAAIIFSDILVIPQAMGMRVEMLEGKGPHFPEPLRNPEDLQTVLDYKVDVLKELDWAFKAITMTRIKLDGEVPLFGFCGGPWTLMVYMTEGGGSRLFRFAKQWINMYPELSHKLLQKITDVAVEFLSQQVVAGAQILQVFESWGGELSSVDFDEFSLPYLRQIAERVPKRLQELGIMEQIPMIVFAKGSWYALDKLCCSGFDVVSLDWSWDPREAVKINKNRVTLQGNLDPGVMYGSKEVITKKVKQMIEAFGGGKSRYIVNFGHGTHPFMDPDVIKFFLEECHRIGSK | |