| Anti-CRISPR ID: | anti_CRISPR3639 |
| Accession: | WP_000384271.1 |
| Anti-CRISPR type: | II-A |
| Family: | AcrIIA21 |
| Organism: | |
| Taxonomy: | Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae. |
| Uniprot entry: | Q8E7D9 |
| Uniprot entry name: | Q8E7D9_STRA3 |
| Structure: | -- |
| Inhibition stage: | |
| Complexed with: | |
| Interactor (DIP): | -- |
| Interactor (STRING): | 211110.gbs0215 |
| Protein sequence: | MDYDNENYLIPKILLQDDFYSSLSAKDILVYAVLKDRQIEALE KGWIDTDGSIYLNFKLIELAKMFSCSRTTMIDVMQRLEEVNLI ERERVDVFYGYSLPYKTYINEV |
| Length of sequence: | 108 |
| Verified: | Verified |
| Comments: | AcrIIA21 inhibits SpyCas9, Streptococcus aureus Cas9 (SauCas9) and SinCas9 with low potency |
| Pubmed: | PMID:32286628 Eitzinger S, Asif A, Watters KE, et al. Machine learning predicts new anti-CRISPR proteins. Nucleic Acids Res. 2020;48(9):4698‐4708. |
| Locus tag: | -- |
| Coding region: | -- |
| Gene name: | gbs0215 |
| Gene ID: | -- |
| Gene Sequence: | ATGGACTATGATAACGAAAACTACTTAATACCTAAGATTTTACTACAAGATGATTTCTACAGTAGTCTATCTGCGAAAGATATTTTAGTCTATGCTGTCTTGAAAGATAGACAGATAGAAGCTCTTGAAAAAGGTTGGATAGATACTGATGGCAGTATATATCTAAATTTTAAACTGATTGAATTAGCTAAAATGTTTTCTTGCAGCAGAACCACAATGATAGATGTTATGCAACGATTGGAAGAAGTTAATTTGATTGAACGAGAAAGAGTAGACGTTTTTTATGGCTACTCTTTACCCTACAAAACCTATATCAACGAGGTATAA |
Anti-CRISPRdb
Database of anti-CRISPR proteins