| Anti-CRISPR ID: | anti_CRISPR1284 |
| Accession: | AVO22749.1 |
| Anti-CRISPR type: | II-A |
| Family: | AcrIIA6 |
| Organism: | |
| Taxonomy: | Viruses; dsDNA viruses, no RNA stage; Caudovirales; Siphoviridae; Sfi21dt1virus; unclassified Sfi21dt1virus |
| Uniprot entry: | A0A2U7VKE8 |
| Uniprot entry name: | A0A2U7VKE8_9CAUD |
| Structure: | 6RJ9: 6RJA: 6RJG: |
| Inhibition stage: | |
| Complexed with: | |
| Interactor (DIP): | -- |
| Interactor (STRING): | -- |
| Protein sequence: | MKINDDIKELILEYMSRYFKFENDFYKLPGIKFTDANWQKFKNGGTDIEKMGAARVNAMLDCLFDDFELAMIGKAQTNYYNDNSLKMNMPFYTYYDMFKKQQLLKWLKNNRDDVIGGTGRMYTASGNYIANAYLEVALESSSLGSGSYMLQMRFKDYSKGQEPIPSGRQNRLEWIENNLENIR |
| Length of sequence: | 183 |
| Verified: | Verified |
| Comments: | It from S. thermophilus phages inhibit Cas9-mediated genome editing of human cells |
| Pubmed: | PMID:30046034 Hynes Alexander P,Rousseau Geneviève M,Agudelo Daniel et al. Widespread anti-CRISPR proteins in virulent bacteriophages inhibit a range of Cas9 proteins.[J] .Nat Commun, 2018, 9: 2919. |
| Locus tag: | D1811_026 |
| Coding region: | MH000604.1:24153..24704 |
| Gene name: | D1811_026 |
| Gene ID: | -- |
| Gene Sequence: | ATGAAAATAAATGACGACATCAAAGAGTTAATTTTAGAATATATGAGCCGTTACTTCAAATTCGAGAACGACTTTTATAAACTGCCAGGCATCAAGTTCACTGATGCAAATTGGCAGAAGTTCAAAAATGGAGGCACTGACATTGAGAAGATGGGGGCGGCACGAGTAAACGCCATGCTCGACTGCCTATTCGACGATTTCGAGCTTGCTATGATTGGCAAGGCTCAAACTAATTATTACAATGATAATTCACTAAAGATGAACATGCCATTTTACACTTACTATGACATGTTCAAAAAGCAGCAACTTCTAAAATGGCTTAAAAATAACCGTGATGATGTCATCGGCGGAACTGGTAGGATGTACACAGCAAGTGGTAATTACATTGCTAACGCTTATTTAGAGGTGGCATTAGAATCGAGCTCGCTTGGTAGTGGCTCTTACATGCTTCAAATGAGGTTTAAAGACTATTCAAAAGGTCAAGAACCTATTCCGTCAGGTCGTCAGAATCGACTTGAATGGATTGAAAACAATCTCGAAAACATTCGATAA |
Anti-CRISPRdb
Database of anti-CRISPR proteins