| Anti-CRISPR ID: | anti_CRISPR0560 |
| Accession: | VDB32351.1 |
| Anti-CRISPR type: | II-A |
| Family: | AcrIIA9 |
| Organism: | |
| Taxonomy: | metagenome unclassified sequences; metagenomes. |
| Uniprot entry: | -- |
| Uniprot entry name: | -- |
| Structure: | -- |
| Inhibition stage: | |
| Complexed with: | |
| Interactor (DIP): | -- |
| Interactor (STRING): | -- |
| Protein sequence: | MKGTEHFKQTIKEYLDGRAQTDELFAVSYAKENKNLDDCITFILNQVKASGCCGMTDDEVWSLAIHYYDEDNIDVGNPISCGVVVNHKVELTEEEKAQARKEALKAYQEEEMRKIQQRHSKPKPTAKAAQSNQTELSLFDF |
| Length of sequence: | 141 |
| Verified: | Verified |
| Comments: | It inhibit SpCas9 activity in our in vitro DNA cleavage assay |
| Pubmed: | PMID:30737174 Uribe Ruben V,van der Helm Eric,Misiakou Maria-Anna et al. Discovery and Characterization of Cas9 Inhibitors Disseminated across Seven Bacterial Phyla.[J] .Cell Host Microbe, 2019, 25: 233-241.e5. |
| Locus tag: | -- |
| Coding region: | LR030269.1:1..426 |
| Gene name: | -- |
| Gene ID: | -- |
| Gene Sequence: | ATGAAAGGTACGGAACATTTCAAACAGACTATCAAGGAATACTTGGACGGCAGGGCGCAGACAGACGAACTTTTTGCTGTCTCCTATGCCAAAGAAAACAAGAACTTGGACGATTGTATCACGTTTATTCTCAATCAAGTAAAGGCAAGCGGCTGTTGCGGAATGACTGACGACGAGGTGTGGTCGCTCGCCATTCATTACTATGATGAAGACAACATCGACGTAGGAAACCCCATTAGCTGCGGTGTCGTGGTCAACCACAAAGTAGAACTGACCGAAGAAGAAAAGGCACAGGCACGAAAGGAGGCGCTGAAAGCCTATCAGGAGGAAGAAATGCGCAAGATACAGCAACGCCACAGCAAGCCGAAGCCGACTGCCAAAGCCGCACAGAGCAACCAAACAGAACTTTCACTTTTCGATTTCTGA |
Anti-CRISPRdb
Database of anti-CRISPR proteins